New clinical study with AlphaWave® L- Theanine confirms stress reduction in healthy adults

A new triple blind, placebo controlled clinical study, published in Neurology and Therapy finds that AlphaWave® increases frontal alpha power, an indication of relaxation without drowsiness, in addition to other objective markers of reduced stress and tension. This is the second study to confirm the relaxation benefits of AlphaWave® L-Theanine.

To read the full article click here
To access the full study click here

Worldwide shipping delays: where we stand at ENI

Date: 08 September, 2021


Almost every company in our industry has been impacted in some way by the current situation of worldwide shipping delays.

At Ethical Naturals (ENI) we’ve been preparing for this since Covid began in early 2020: working with our key manufacturers to build inventory and assure ongoing supply to our regular customers. In a recent interview for NutraIngredients, Cal Bewicke, ENI CEO, talked about our inventory position today:

‘As soon as Covid began, we progressively built more inventory, planning six, nine months ahead. That’s worked well for us, and we’ve been shipping out pretty much on time throughout this period.

We always carry substantial inventory; now it’s even larger. A number of companies rely on our proprietary ingredients like AlphaWave® L-Theanine, GreenGrown® Glucosamine, and the core botanical extracts that we supply. We won’t let those companies down.’

In answer to the question: ‘When do you anticipate it will return to normal?’ Cal stated:

‘Someday I expect we’ll return to a ‘new normal’, but I can’t say when that will be. The positive that’s come out of this situation is that many of us have come to see again the value of strong, dependable and well-invested supply chains at every level. That’s the way we move forward, by supporting each other in the quality investments of time and resources that we make into our industry. This goes for every step in the supply chain, from the field to the finished products.’


At ENI, we work to support your work.
The Team at Ethical Naturals

Links to two articles of interest:
"Port snarl in China shows shipping crisis from far over"
"A record-breaking 44 container ships are stuck off the coast of California".

Polyphenol-C™: a new premium vitamin-C provides wide-spectrum berry polyphenols for enhanced immune support

It’s been known for centuries that eating fruits prevented scurvy, but it wasn’t until 1930 Albert Szent-Gyorzi was awarded the Nobel Prize for discovering the identity of the vitamin-C molecule. The name given to it, ‘ascorbic acid’ literally means ‘anti-scurvy’.

To read the full article click here.

VinCare Clinical Study: Whole Grape Extract Supports Healthy Cholesterol and Cardiovascular Health

Grape extracts growing popularity

Grape extracts of all kinds: skin, seed and whole grape are reaching a new level of popularity with supplement buying consumers. This may be because we’re dealing with the new lifestyle challenges of today, when the extract benefits that support cardiovascular health and anti-oxidant activity mean even more to us than they did a year ago

To read the full article click here.

Cranberry’s unique A-Type PAC’s show significant UTH benefits through anti-adhesion acitvity (AAA)

Cranberry: the journey through nature and science

Cranberries, the beautiful red fruits of Vaccinium macrocarpon ​have been valued for many centuries for both their food and medicinal qualities. Indigenous to N.America, cranberries were widely used by Native Americans. They quickly became popular with settlers from Europe, and in 1672, in one of the earliest records of medicinal use, John Josselyn described Cranberries as being an excellent protection against scurvy [1]. By 1789 the fruit was so in demand that the New Jersey legislature restricted the harvesting of berries.

To read the full article click here.

GreenGrown® glucosamine is USP grade, Non-GMO and Kosher Certified, protected by 20 patents

Glucosamine: history and nature

Glucosamine was first identified and prepared in 1876 by Georg Ledderhose, through a process that involved the hydrolysis of chitin with concentrated hydrochloric acid. However it wasn’t until the 1960’s that its potential application in joint care was discovered in Italy by Professor Luigi Rovati, the founder of the pharmaceutical giant RottaPharm-Madaus.

To read the full article click here.

Polyphenol-C®: a new premium vitamin C for today provides wide-spectrum berry polyphenols

In 1747 James Lind conducted one of the first placebo controlled clinical trials on record when he tested 6 groups of sailors suffering from scurvy, with six different treatment regimens. Only oranges, lemons and limes were effective. Thereafter, British ships began carrying barrels of limes (when available) to prevent scurvy. Thus, in ports and countries around the world the English came to be known as ‘Limeys’.

To read the full article click here.

Alpha brainwaves: the key to the deep relaxation and the focused energy we need today?

L-Theanine and the mystery of tea 

Tea, the beverage made from Camellia sinensis,​ has been drunk for its beneficial effects for millennia. Legend has it that the Chinese emperor and herbalist Shennong discovered tea in 2737 BC. Shenong was famous for his wise edicts, and one such edict required that people boil their water before drinking it. This process lead, indirectly to the infusion of Camellia​ leaves to make the first tea.

To read the full article click here.

ENI’s GreenGrown® Vegetable Source Glucosamine now protected by 21 patents in 12 countries!

Now 21 patents cover manufacturing and identity testing of ENI's GreenGrown® material in the U.S., China, Germany, France, UK, Netherlands, Japan, Mexico, Australia, Brazil, Canada and Korea. In addition to covering manufacturing by fermentation, ENI has developed a method to discern shellfish-based from vegetable-based glucosamine. Their new Isotopic Signature Carbon Tracing (ISCT) method differentiates between the molecules from either source, though they are virtually identical. As the popularity of vegan and vegetarian supplements grows, this identity and quality assurance step becomes more important. “Today, manufacturers are often attempting to produce glucosamine by fermentation in the same facilities used for shellfish-based material, and intentional or unintentional adulteration can occur,” says Cal Bewicke, CEO of ENI. “That’s why every batch of our material is tested through the ISTC method to guarantee the 100% vegetable source.” Great news for vegans and vegetarians alike!

To read the full article click here.

Botanical Extracts: Is there a war out there?

ENI’s co-founder and CEO was recently published in the 2018 NBJ “Dark Issue” in an article entitled ‘Botanical Extracts: Is there a war out there? A Report from the front lines.’   Cal’s article sheds light on the real quality issues in our botanical extract supply. He looks at how key brands, suppliers and industry associations are working to make a difference through rigorous quality testing, and also how the focus on cheap ingredients leads to serious adulteration problems in the products used by millions of consumers

To read the full article click here.

Cranberry Excellence

Author: Cal Bewicke

Well, Cranberry continues to gain attention in the news as the #2 most popular botanical in the country. Very good to see the new ABC Botanical Adulteration Program report on Cranberry, that also addressed the great variability in Cranberry supplement products today; many that are made only from simple juice concentrates or left over ‘press cake’! The report also talks about recent developments in quality and differentiation using analysis by the BL-DMAC method, that best quantifies the active ‘A-linked’ PAC’s. If anyone would like a copy of the Cranberry Report, please contact This email address is being protected from spambots. You need JavaScript enabled to view it., and we’ll send it over. It’s a very interesting read.

So, this is one more confirmation of the quality built into our Cranberex™, Oregon Cranberry Extract; a 200X concentration of the whole fruit, tested by BL-DMAC to contain 15% A-linked PAC’s. We use Oregon cranberry because the cool micro-climate of the coastal area produces dark red cranberries that are particularly rich in the valuable PAC’s.

My guess is that life on the Oregon Coast now is wet and windy. But being a part of the cranberry harvest in Bandon, Oregon is a special experience, and we’ll be up there for harvest again later in the year (when I expect the weather may be about the same!).


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Ethical Naturals Inc., is certified to comply with NSF GMP Registration Program Requirements of NSF/ANSI 173, Section 8 which includes FSMA and cGMP (21 CFR 111), (21 CFR 117).

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